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Targeting tumor suppressor genes for cancer therapy.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Dec 2015

Liu Yunhua, Hu Xiaoxiao, Han Cecil, Wang Liana, Zhang Xinna, He Xiaoming, Lu Xiongbin

Abstract excerpt

Cancer drugs are broadly classified into two categories: cytotoxic chemotherapies and targeted therapies that specifically modulate the activity of one or more proteins involved in cancer. Major advances have been achieved in targeted cancer therapies in the past few decades, which is ascribed to the increasing understanding of molecular mechanisms for cancer initiation and progression. Consequently, monoclonal...

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Antineoplastic Agents
Drug Discovery
BRCA1 gene
PTEN gene
Genes, Tumor Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26445307
DOI: 10.1002/bies.201500093
PMCID: PMC8638220

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BRCA1
PTEN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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