Article

CIT tumor lines: A novel series of immunogenic cutaneous squamous cell carcinoma cell lines derived from chemical carcinogenesis

2025-04-08

Abstract excerpt

Immunotherapy is now widely used to treat advanced-stage skin cancer, but it is effective for only approximately half of skin cancer patients, including both patients with melanoma and cutaneous squamous cell carcinoma (cSCC). To overcome current barriers, preclinical mouse models that faithfully recapitulate the tumor genetics, mutation burdens, and neoantigen patterns of specific human tumor types are essential....

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Identifiers and source

Literature Corpus work: 6357f629-d5a2-5143-96bf-26f840a328b9
DOI: 10.1101/2025.04.03.647071

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