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Article

From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma.

The Journal of clinical investigation - 1 Feb 2012

Ratushny Vladimir, Gober Michael D, Hick Ryan, Ridky Todd W, Seykora John T

Abstract excerpt

Cutaneous squamous cell carcinoma (cSCC) is the second most common human cancer with over 250,000 new cases annually in the US and is second in incidence only to basal cell carcinoma. cSCC typically manifests as a spectrum of progressively advanced malignancies, ranging from a precursor actinic keratosis (AK) to squamous cell carcinoma (SCC) in situ (SCCIS), invasive cSCC, and finally metastatic SCC. In this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22293185
DOI: 10.1172/JCI57415
PMCID: PMC3266779

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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