Article

Comparative cortical transcriptomic profiling of Alzheimer’s disease, vascular dementia and mixed dementia

2025-09-12

Abstract excerpt

Alzheimer’s disease (AD) and vascular dementia (VaD) are two of the commonest causes of dementia worldwide. While AD is characterized by amyloid plaque and neurofibrillary tangle formation, and VaD is characterized by cerebrovascular disease (CeVD), these pathophysiological processes frequently coexist, leading to mixed AD+VaD dementia (MIX). At present, it is unclear which of the multiple gene expression changes...

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Literature Corpus work: 6332ee59-ab9e-53eb-9715-df0812bf194f
DOI: 10.1101/2025.09.11.25335564

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