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Genome-wide association analysis identifies ancestry-specific genetic variation associated with medication response in the Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH)

2022-01-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Characterization of genetic variation that influences response to glucose-lowering medications is instrumental to precision medicine for treatment of type 2 diabetes (T2D). SUGAR-MGH examined the acute response to two anti-diabetes medications in order to understand the functional relevance of known T2D- and glycaemic trait-associated genetic loci. <h4>Methods</h4> 1,000 parti...

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Literature Corpus work: 632b2e5e-bacf-52ca-9adb-975b028df115
DOI: 10.1101/2022.01.24.22269036

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