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Article

Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH.

Diabetologia - 1 Jul 2023

Li Josephine H, Brenner Laura N, Kaur Varinderpal, Figueroa Katherine, Schroeder Philip, Huerta-Chagoya Alicia, Udler Miriam S, Leong Aaron, Mercader Josep M, Florez Jose C

Abstract excerpt

AIMS/HYPOTHESIS: Characterisation of genetic variation that influences the response to glucose-lowering medications is instrumental to precision medicine for treatment of type 2 diabetes. The Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans (SUGAR-MGH) examined the acute response to metformin and glipizide in order to identify new pharmacogenetic associations for the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37233759
DOI: 10.1007/s00125-023-05922-7
PMCID: PMC10790310

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ZMIZ1

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