Article

Stochastic Modeling Reveals Kinetic Heterogeneity in Post-replication DNA Methylation

2019-06-19

Abstract excerpt

DNA methylation is a heritable epigenetic modification that plays an essential role in mammalian development. Genomic methylation patterns are dynamically maintained, with DNA methyltransferases mediating inheritance of methyl marks onto nascent DNA over cycles of replication. A recently developed experimental technique employing immunoprecipitation of bromodeoxyuridine labeled nascent DNA followed by bisulfite se...

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Literature Corpus work: 6307b3a8-1874-5126-a1e7-abf166fca59f
DOI: 10.1101/677013

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