Article

Convergent genomic and molecular features predict risk of metachronous metastasis in clear cell renal cell carcinoma

2025-01-08

Abstract excerpt

Understanding the molecular features that determine the risk of metachronous metastases in clear cell renal cell carcinoma (ccRCC) is crucial for improving adjuvant treatment strategies and patient outcomes. We identified convergent genomic and transcriptomic alterations in chromosome 1p, implicating dysregulation of epithelial cell polarity and fatty acid metabolism as novel risk factors for metachronous metastas...

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Literature Corpus work: 62f61da5-03c5-589a-bf2a-07ae045cf2b2
DOI: 10.1101/2025.01.07.630976

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