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Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma

18 Apr 2018

Abstract excerpt

BACKGROUND: The genomic landscape of primary clear cell renal cell carcinoma (ccRCC) has been well described. However, little is known about cohort genomic alterations (GA) landscape in ccRCC metastases, or how it compares to primary tumours in aggregate. The genomic landscape of metastases may have biological, clinical, and therapeutic implications. METHODS: We collected targeted next-generation sequencing...

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PMID: 29674707
DOI: 10.1038/s41416-018-0064-3

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