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Article

Multi-regional Sequencing Elucidates the Evolution of Clear Cell Renal Cell Carcinoma.

Cell - 19 Apr 2018

Ricketts Christopher J, Linehan W Marston

Abstract excerpt

Extensive multi-regional whole-genome and -exome sequencing performed in tumors from patients with localized, as well as metastatic, clear cell renal cell carcinoma provides a comprehensive description of the tumor origin, intratumoral heterogeneity, evolution, and route to metastasis, laying the foundation for the development of precision clinical management.

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Identifiers

PMID: 29677504
DOI: 10.1016/j.cell.2018.03.077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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