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Article

Pharmacogenomics of Arylamine N-acetyltransferase.

2004-09-01

Abstract excerpt

The arylamine N-acetyltransferases (NATs) are a unique family of enzymes that catalyse the transfer of an acetyl group from acetyl CoA to the terminal nitrogen of hydrazine and arylamine xenobiotics. They have well characterised roles in drug detoxification and carcinogen activation and NAT homologues are present in numerous species from bacteria to humans. The importance of human NAT in xenobiotic metabolism is w...

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Literature Corpus work
34947ff4-2f97-5f5c-8176-dc5d5d7c27f9
DOI
10.2174/1570160043377448
Open publication

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