Article
Pharmacogenetics of the arylamine N-acetyltransferases.
The pharmacogenomics journal - 1 Jan 2002
Butcher N J, Boukouvala S, Sim E, Minchin R F
Abstract excerpt
The arylamine N-acetyltransferases (NATs) are involved in the metabolism of a variety of different compounds that we are exposed to on a daily basis. Many drugs and chemicals found in the environment, such as those in cigarette smoke, car exhaust fumes and in foodstuffs, can be either detoxified by NATs and eliminated from the body or bioactivated to metabolites that have the potential to cause toxicity and/or...
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