Article

Sting orchestrates the crosstalk between polyunsaturated fatty acids metabolism and inflammatory responses

2020-12-23

Abstract excerpt

<h4>Summary</h4> Inflammatory disorders are major health issues in which immune function and metabolic homeostasis are concertedly altered. Yet, the molecular mechanisms coordinating innate and metabolic pathways in homeostatic conditions are poorly understood. Here, we unveil a negative regulatory feedback loop involving the Stimulator of interferon genes (Sting) and the Fatty acid desaturase 2 (Fads2). At stead...

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Identifiers and source

Literature Corpus work: 62a8c4dc-f406-58db-adef-a57bb563fcf5
DOI: 10.1101/2020.12.22.423950

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