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Article

The role of the cGAS-STING pathway in metabolic diseases

1 Jun 2024

Abstract excerpt

The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway is a critical innate immune pathway primarily due to its vital DNA sensing mechanism in pathogen defence. Recent research advances have shown that excessive activation or damage to the cGAS-STING pathway can exacerbate chronic inflammatory responses, playing a significant role in metabolic dysfunction and aging, leading to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38988528
DOI: 10.1016/j.heliyon.2024.e33093

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