Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The cGAS-cGAMP-STING Pathway: A Molecular Link Between Immunity and Metabolism

13 May 2019

Abstract excerpt

It has been appreciated for many years that there is a strong association between metabolism and immunity in advanced metazoan organisms. Distinct immune signatures and signaling pathways have been found not only in immune but also in metabolic cells. The newly discovered DNA-sensing cGAS-cGAMP-STING pathway mediates type I interferon inflammatory responses in immune cells to defend against viral and bacterial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Mosquito-borne diseases and control
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31109939
DOI: 10.2337/dbi18-0052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The cGAS-cGAMP-STING Pathway: A Molecular Link Between Immunity and MetabolismPMID 31109939Read ↗

The role of the cGAS-STING pathway in metabolic diseasesSemantic proximity Read ↗

Significance of the cGAS-STING Pathway in Health and DiseaseSemantic proximity Read ↗

A Variety of Nucleic Acid Species Are Sensed by cGAS, Implications for Its Diverse FunctionsSemantic proximity Read ↗

Mitochondrial DNA-triggered innate immune response: mechanisms and diseasesSemantic proximity Read ↗

Beyond DNA sensing: expanding the role of cGAS/STING in immunity and diseasesSemantic proximity Read ↗

Research Advances in How the cGAS-STING Pathway Controls the Cellular Inflammatory ResponseSemantic proximity Read ↗

The multifaceted functions of cGASSemantic proximity Read ↗

The triggers of the cGAS-STING pathway and the connection with inflammatory and autoimmune diseasesSemantic proximity Read ↗

Regulation of cGAS‐Mediated Immune Responses and ImmunotherapySemantic proximity Read ↗

Pathophysiological Roles of the cGAS-STING Inflammatory PathwaySemantic proximity Read ↗

The cGAS-STING pathway: a dual regulator of immune response in cancer and therapeutic implicationsSemantic proximity Read ↗

Function and regulation of cGAS-STING signaling in infectious diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.