Article

From Mutations to Disease: Computational Analysis and Interpretation of GPCR-Associated Pathogenicity

2024-06-17

Abstract excerpt

<h4>ABSTRACT</h4> G protein-coupled receptors (GPCRs) perform critical roles in numerous physiological processes and their mutations are, therefore, associated with various human diseases. Hence, understanding the molecular consequences of pathogenic mutations in GPCRs is essential for elucidating disease mechanisms and developing effective therapeutic strategies. In this study, we employed computational approach...

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Literature Corpus work: 6283898f-10d7-5027-9299-8ab9dfd0d884
DOI: 10.1101/2024.06.17.599437

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