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Article

Sequence variation in G-protein-coupled receptors: analysis of single nucleotide polymorphisms.

Nucleic acids research - 1 Jan 2005

Balasubramanian Suganthi, Xia Yu, Freinkman Elizaveta, Gerstein Mark

Abstract excerpt

We assessed the disease-causing potential of single nucleotide polymorphisms (SNPs) based on a simple set of sequence-based features. We focused on SNPs from the dbSNP database in G-protein-coupled receptors (GPCRs), a large class of important transmembrane (TM) proteins. Apart from the location of the SNP in the protein, we evaluated the predictive power of three major classes of features to differentiate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15784611
DOI: 10.1093/nar/gki311
PMCID: PMC1069129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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