Article

Tumour-intrinsic features shape T-cell differentiation through myeloma disease evolution

2024-06-23

Abstract excerpt

The haematological malignancy multiple myeloma is associated with skewed T-cell activation and function. T-cell alterations are detectable in asymptomatic myeloma precursor conditions and have the potential to identify precursor patients at imminent risk of progression. However, what myeloma-associated T-cells alterations represent mechanistically, how they relate to tumour burden and gene expression, and what inf...

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Identifiers and source

Literature Corpus work: 62171c7c-86d8-5f4d-81df-53e4fffa647d
DOI: 10.1101/2024.06.22.24309250

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