Article
SorLA restricts TNFα release from microglia to shape glioma-supportive brain microenvironment
2023-04-12
Abstract excerpt
SorLA, encoded by the gene SORL1 , is an intracellular sorting receptor of the VPS10P domain receptor gene family. Although SorLA is best recognized for its ability to shuttle target proteins between intracellular compartments in neurons, recent data suggest that also its microglial expression can be of high relevance for the pathogenesis of brain diseases, including glioblastoma (GBM). Here we interrogated the i...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 61e737bf-e161-569a-8e84-b496929b717e
- DOI
- 10.1101/2023.04.12.536447