Article

SMAC mimetics drive microglia phenotype and glioblastoma immune microenvironment

2024-04-12

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Tumor-associated macrophages/microglia (TAMs) are highly plastic and heterogeneous immune cells that can be immune-supportive or tumor-supportive depending on the microenvironment. TAMs are the most abundant immune cells in glioblastoma (GB) and play a key role in immunosuppression. Therefore, TAMs reprogramming toward immune-supportive cells is a promising st...

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Literature Corpus work: a58aa05e-d706-59a8-9561-75467454c422
DOI: 10.21203/rs.3.rs-3791903/v2

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