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The actin nucleation factors JMY and WHAMM enable a rapid p53-dependent pathway of apoptosis

2020-07-16

Abstract excerpt

The actin cytoskeleton is a well-known player in most vital cellular processes, but comparably little is understood about how the actin assembly machinery impacts programmed cell death pathways. In the current study, we explored roles for the human W iskott- A ldrich S yndrome P rotein (WASP) family of actin nucleation factors in DNA damage-induced apoptosis. Inactivation of each WASP-family gene revealed that...

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Identifiers and source

Literature Corpus work
0e4f47a3-9636-5a15-9f95-9745d5f00f59
DOI
10.1101/2020.07.15.205518
Open publication

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The actin nucleation factors JMY and WHAMM enable a rapid p53-dependent pathway of apoptosisDOI 10.1101/2020.07.15.205518
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