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The Role of WAVE2 Signaling in Cancer

14 Sept 2021

Abstract excerpt

The Wiskott-Aldrich syndrome protein (WASP) and WASP family verprolin-homologous protein (WAVE)-WAVE1, WAVE2 and WAVE3 regulate rapid reorganization of cortical actin filaments and have been shown to form a key link between small GTPases and the actin cytoskeleton. Upon receiving upstream signals from Rho-family GTPases, the WASP and WAVE family proteins play a significant role in polymerization of actin...

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Identifiers

PMID: 34572403
DOI: 10.3390/biomedicines9091217

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