Article

A programmable arthritis-specific receptor for guided articular cartilage regenerative medicine

2024-02-04

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Investigational cell therapies have been developed as disease-modifying agents for the treatment of osteoarthritis (OA), including those that inducibly respond to inflammatory factors driving OA progression. However, dysregulated inflammatory cascades do not specifically signify the presence of OA. Here, we deploy a synthetic receptor platform that regulates cell behaviors in...

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Literature Corpus work: 61cd54c1-11e0-5c2e-9ab7-f7044d95aa7f
DOI: 10.1101/2024.01.31.578281

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