Article

Alternate RNA decoding results in stable and abundant proteins in mammals

2024-08-26

Abstract excerpt

Amino acid substitutions may substantially alter protein stability and function, but the contribution of substitutions arising from alternate translation (deviations from the genetic code) is unknown. To explore it, we analyzed deep proteomic and transcriptomic data from over 1,000 human samples, including 6 cancer types and 26 healthy human tissues. This global analysis identified 60,803 fragmentation spectra cor...

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Literature Corpus work: 6125802b-a12c-5c9d-9292-bd643d541f0d
DOI: 10.1101/2024.08.26.609665

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