Article

Encoded and non-genetic alternative protein variants expand human functional proteome

2025-02-17

Abstract excerpt

Each stage of the Central Dogma contributes to proteome diversity through mechanisms such as heterozygosity, somatic mutations, transcriptional errors, and translational errors. As a result, a diverse array of protein variants can coexist within a single proteome, such as that of humans. However, until now, methods to detect, quantify, and evaluate the functional consequences of these variants have been lacking. H...

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Literature Corpus work: f7fe3d19-91af-5c02-b450-4ca917400dce
DOI: 10.1101/2025.02.17.638604

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