Article

Alternatively Spliced Dual-Coding Regions Contribute to the Human Gene Regulatory Program

2026-02-25

Abstract excerpt

In eukaryotes, alternative splicing allows a single gene to encode multiple protein isoforms, by conditionally using only a subset of the gene’s exons. In some cases, distinct isoforms utilize the same exon(s) in a different reading frame, thus encoding a distinct sequence of amino acids. Here, we provide a genome-wide view of such dual coding regions (DCRs) in humans. By mapping all reviewed human UniProtKB/Swiss...

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Literature Corpus work: 737adde0-14b2-5427-8d98-39e9e0654b93
DOI: 10.64898/2026.02.24.707805

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