Article

Genome-wide transcriptome and translatome analyses reveal the role of protein extension and domestication in liver cancer oncogenesis

2021-02-10

Abstract excerpt

<h4>ABSTRACT</h4> One gene could be transcribed to different RNA isoforms, and then produce various forms of protein sequences. This mechanism largely diversifies the cellular pool and allows natural selection to select from a wider range of substrates. Most of the deleterious changes should be either purged or only be observed in patients with deficiencies or diseases. In the cancer field, the “intra-gene” chang...

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Literature Corpus work: 424c6fb4-8326-56dc-8e80-b3d1194d1513
DOI: 10.1101/2021.02.10.430565

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