Article

Investigating the effect of chronic activation of AMP-activated protein kinase in the liver

2018-01-01

Abstract excerpt

Obesity and its associated complications, are an increasing global problem. Non-alcoholic fatty liver disease (NAFLD), the hepatic component of the Metabolic Syndrome currently affects an estimated 25% of the world's population, with 2% of those affected dying from a NAFLD liver related cause, such as hepatocellular cancer (HCC). AMP-activated protein kinase (AMPK), a master regulator of energy homeostasis that re...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 6116eaa6-6b1c-5a5f-969d-32d7d6cb645c
DOI: 10.25560/66951

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Investigating the effect of chronic activation of AMP-activated protein kinase in the liverDOI 10.25560/66951Read

Liver-Specific Activation of AMPK Prevents Steatosis on a High-Fructose Diet.Semantic proximity Read

AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease.Semantic proximity Read

Advances in the research of AMPK and its subunit genes.Semantic proximity Read

Investigating the regulation of AMP-activated protein kinase and SNF1Semantic proximity Read

Investigating the regulation of AMP-activated protein kinaseSemantic proximity Read

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism.Semantic proximity Read

Fine-tuning AMPK in physiology and disease using point-mutant mouse modelsSemantic proximity Read

Energy Homeostasis and Cancer Prevention: The AMP-Activated Protein KinaseSemantic proximity Read

AMP-activated protein kinase – not just an energy sensorSemantic proximity Read

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function.Semantic proximity Read

Direct β1/ β2 AMPK activation reduces liver steatosis but not fibrosis in a mouse model of non-alcoholic steatohepatitisSemantic proximity Read

Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease.Semantic proximity Read