Article

Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells

2022-03-19

Abstract excerpt

<h4>ABSTRACT</h4> Aggregates of the tau protein are a well-known hallmark of several neurodegenerative diseases, collectively referred as tauopathies, including frontal temporal dementia and Alzheimer’s disease (AD). Monitoring the transformation process of tau from physiological monomers into pathological oligomers or aggregates in a high-throughput, quantitative manner and in a cellular context is still a major...

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Literature Corpus work: 60fe662a-854a-516a-8d7b-e227c550c42a
DOI: 10.1101/2022.03.18.484918

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