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Associations between the <i>Plasmodium falciparum</i> genome and sickle haemoglobin identified in mild malaria cases from Ghana

2023-09-14

Abstract excerpt

<h4>Background</h4> Heterozygosity for sickle haemoglobin (HbS) confers protection against severe malaria caused by the parasite Plasmodium falciparum. Recent work has suggested that this protective effect can depend on the parasite genotype: P. falciparum sickle-associated ( Pfsa ) variants were found disproportionately in individuals with severe malaria carrying HbS alleles in The Gambia and Kenya. Interacti...

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Literature Corpus work
60bedae9-813b-58ee-b8cc-31ac299ea66b
DOI
10.1101/2023.09.14.557461
Open publication

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Associations between the <i>Plasmodium falciparum</i> genome and sickle haemoglobin identified in mild malaria cases from GhanaDOI 10.1101/2023.09.14.557461
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