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Article

Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease.

Journal of neurochemistry - 1 Dec 2002

Haughey Norman J, Nath Avi, Chan Sic L, Borchard A C, Rao Mahendra S, Mattson Mark P

Abstract excerpt

Neurogenesis occurs in the adult mammalian brain and may play roles in learning and memory processes and recovery from injury, suggesting that abnormalities in neural progenitor cells (NPC) might contribute to the pathogenesis of disorders of learning and memory in humans. The objectives of this study were to determine whether NPC proliferation, survival and neuronal differentiation are impaired in a transgenic...

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Identifiers

PMID: 12472904
DOI: 10.1046/j.1471-4159.2002.01267.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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