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Article

CHRNA5 links chandelier cells to protection against amyloid pathology in human aging and Alzheimer's Disease

2022-09-06

Abstract excerpt

<title>Abstract</title> <p>Changes in high-affinity nicotinic acetylcholine receptors are intricately connected to neuropathology in Alzheimer’s Disease (AD). Protective and cognitive-enhancing roles for the nicotinic α5 subunit have been identified, but this gene has not been closely examined in the context of human aging and dementia. Therefore, we investigate the nicotinic α5 gene <italic>CHRNA5</italic> and t...

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Identifiers and source

Literature Corpus work
60a05255-51cd-531f-84be-203463063627
DOI
10.21203/rs.3.rs-2011761/v1
Open publication

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CHRNA5 links chandelier cells to protection against amyloid pathology in human aging and Alzheimer's DiseaseDOI 10.21203/rs.3.rs-2011761/v1
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