Article

Structural variants linked to Alzheimer’s Disease and other common age-related clinical and neuropathologic traits

2024-08-13

Abstract excerpt

<h4>ABSTRACT</h4> Advances have led to a greater understanding of the genetics of Alzheimer’s Disease (AD). However, the gap between the predicted and observed genetic heritability estimates when using single nucleotide polymorphisms (SNPs) and small indel data remains. Large genomic rearrangements, known as structural variants (SVs), have the potential to account for this missing genetic heritability. By leveragi...

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Literature Corpus work: e7f66f87-0288-5df2-889e-2d87aa4f2928
DOI: 10.1101/2024.08.12.24311887

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