Overdominant Effect of a CHRNA4 Polymorphism on Cingulo-Opercular Network Activity and Cognitive Control.

doi:10.1523/JNEUROSCI.0991-17.2017

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Overdominant Effect of a CHRNA4 Polymorphism on Cingulo-Opercular Network Activity and Cognitive Control.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 4 Oct 2017

Sadaghiani Sepideh, Ng Bernard, Altmann Andre, Poline Jean-Baptiste, Banaschewski Tobias, Bokde Arun L W, Bromberg Uli, Büchel Christian, Burke Quinlan Erin, Conrod Patricia, Desrivières Sylvane, Flor Herta, Frouin Vincent, Garavan Hugh, Gowland Penny, Gallinat Jürgen, Heinz Andreas, Ittermann Bernd, Martinot Jean-Luc, Paillère Martinot Marie-Laure, Lemaitre Hervé, Nees Frauke, Papadopoulos Orfanos Dimitri, Paus Tomáš, Poustka Luise, Millenet Sabina, Fröhner Juliane H, Smolka Michael N, Walter Henrik, Whelan Robert, Schumann Gunter, Napolioni Valerio, Greicius Michael

Abstract excerpt

The nicotinic system plays an important role in cognitive control and is implicated in several neuropsychiatric conditions. However, the contributions of genetic variability in this system to individuals' cognitive control abilities are poorly understood and the brain processes that mediate such genetic contributions remain largely unidentified. In this first large-scale neuroimaging genetics study of the human...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebral Cortex

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cognition

Share to Frontal Lobe

Share to Gyrus Cinguli

Share to Nerve Net

Share to Photic Stimulation

Share to Psychomotor Performance

Share to Receptors, Nicotinic

Source

Open in PubMed Open full text

Identifiers

PMID: 28877969
DOI: 10.1523/JNEUROSCI.0991-17.2017
PMCID: PMC6596609

Genes

CHRNA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overdominant Effect of a CHRNA4 Polymorphism on Cingulo-Opercular Network Activity and Cognitive Control.PMID 28877969Read ↗

A cognitive phenotype for a polymorphism in the nicotinic receptor gene CHRNA4.Semantic proximity Read ↗

Association of Common Polymorphisms in the Nicotinic Acetylcholine Receptor Alpha4 Subunit Gene with an Electrophysiological Endophenotype in a Large Population-Based Sample.Semantic proximity Read ↗

Single nucleotide polymorphism heritability and differential patterns of genetic overlap between inattention and four neurocognitive factors in youth.Semantic proximity Read ↗

Impaired executive control is associated with a variation in the promoter region of the tryptophan hydroxylase 2 gene.Semantic proximity Read ↗

Individual variation in a cholinergic receptor gene modulates attention.Semantic proximity Read ↗

CHRNA5 links chandelier cells to protection against amyloid pathology in human aging and Alzheimer's DiseaseSemantic proximity Read ↗

Allele-dosage genetic polymorphisms of cannabinoid receptor 1 predict attention, but not working memory performance in humans.Semantic proximity Read ↗

Genetic variation in nicotinic receptors affects brain networks involved in reorienting attention.Semantic proximity Read ↗

Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes.Semantic proximity Read ↗

<i>CHRNA5</i> links chandelier cells to severity of amyloid pathology in aging and Alzheimer’s DiseaseSemantic proximity Read ↗

Molecular genetic influences on attentional control and other executive processes and their links with psychopathology in the AFFECT studySemantic proximity Read ↗

Effects of a CACNA1C genotype on attention networks in healthy individuals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.