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Core Needle Biopsy-Derived Organoids for Docetaxel Sensitivity Assessment in HR-Positive/HER2- Negative Breast Cancer: Exploratory Implications of Morphology and Treatment-Induced TUBB3 Dynamic Patterns

2026-08-28

Abstract excerpt

<title>Abstract</title> <p>Background The benefit of taxane-containing neoadjuvant chemotherapy (NAC) in hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer (HR+/HER2 − breast cancer) is variable, and reliable pretreatment functional markers of taxane sensitivity remain limited. Core needle biopsy (CNB)-derived patient-derived tumor organoids (PDTOs) may provide a clinically...

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Literature Corpus work: 660c7685-59fd-57e1-859f-d44b277216ee
DOI: 10.21203/rs.3.rs-10489872/v1

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Core Needle Biopsy-Derived Organoids for Docetaxel Sensitivity Assessment in HR-Positive/HER2- Negative Breast Cancer: Exploratory Implications of Morphology and Treatment-Induced TUBB3 Dynamic PatternsDOI 10.21203/rs.3.rs-10489872/v1Read

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