Article
Microscopy-based phenotypic monitoring of MDA-MB-231 spheroids allows the evaluation of phenotype-directed therapy.
Experimental cell research - 15 Apr 2023
Mahmoud Loay, Cougnoux Antony, Bekiari Christina, Araceli Ruiz de Castroviejo Teba Paloma, El Marrahi Anissa, Panneau Guilhem, Gsell Louise, Hausser Jean
Abstract excerpt
Breast cancer (BC) is the most commonly diagnosed cancer among women. Prognosis has improved over the years, to a large extent, owing to personalized therapy informed by molecular profiling of hormone receptors. However, there is a need for new therapeutic approaches for a subgroup of BCs lacking molecular markers, the Triple Negative Breast Cancer (TNBC) subgroup. TNBC is the most aggressive type of BC, lacks an...
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