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Spatial Transcriptomic Profiling Reveals Microenvironment-Dependent Immune Signatures in a Lyme Arthritis model

2026-06-25

Abstract excerpt

Lyme arthritis, a manifestation of Lyme disease, is triggered by the spirochetal bacterium Borrelia burgdorferi ( Bb ), which is transmitted through the bite of the Ixodes tick. Although multiple studies have been conducted on the complex host immune response in Lyme arthritis, the spatial gene expression environment in the joint tissue remains unexplored. Here, we applied spatial transcriptomics to ankle joint...

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Literature Corpus work
608f8981-b22a-565b-81b7-280f1570db63
DOI
10.64898/2026.06.25.734510
Open publication

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Spatial Transcriptomic Profiling Reveals Microenvironment-Dependent Immune Signatures in a Lyme Arthritis modelDOI 10.64898/2026.06.25.734510
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