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Article

Gene Expression Profiling Reveals Unique Pathways Associated with Differential Severity of Lyme Arthritis

1 Dec 2006

Abstract excerpt

The murine model of Lyme disease provides a unique opportunity to study the localized host response to similar stimulus, Borrelia burgdorferi, in the joints of mice destined to develop severe arthritis (C3H) or mild disease (C57BL/6). Pathways associated with the response to infection and the development of Lyme arthritis were identified by global gene expression patterns using oligonucleotide microarrays. A...

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PMID: 17114465
DOI: 10.4049/jimmunol.177.11.7930

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