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Exploring inflammatory signatures in arthritic joint biopsies with Spatial Transcriptomics

12 Dec 2019

Abstract excerpt

Lately it has become possible to analyze transcriptomic profiles in tissue sections with retained cellular context. We aimed to explore synovial biopsies from rheumatoid arthritis (RA) and spondyloarthritis (SpA) patients, using Spatial Transcriptomics (ST) as a proof of principle approach for unbiased mRNA studies at the site of inflammation in these chronic inflammatory diseases. Synovial tissue biopsies from...

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PMID: 31831833
DOI: 10.1038/s41598-019-55441-y

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