Article
Inter-individual variation of DNA methylation and its implications for large-scale epigenome mapping.
Nucleic acids research - 1 Jun 2008
Bock Christoph, Walter Jörn, Paulsen Martina, Lengauer Thomas
Abstract excerpt
Genomic DNA methylation profiles exhibit substantial variation within the human population, with important functional implications for gene regulation. So far little is known about the characteristics and determinants of DNA methylation variation among healthy individuals. We performed bioinformatic analysis of high-resolution methylation profiles from multiple individuals, uncovering complex patterns of...
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