Article

scHiMe: Predicting single-cell DNA methylation levels based on single-cell Hi-C data

2022-09-16

Abstract excerpt

Recently a biochemistry experiment was developed to simultaneously capture the chromosomal conformations and DNA methylation levels on single cells. A computational tool to predict single-cell methylation levels based on single-cell Hi-C data becomes necessary due to the availability of this experiment. scHiMe was developed to predict the base-pair-specific methylation levels in the promoter regions genome-wide ba...

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Literature Corpus work: ae80eac2-4890-5db7-8619-470c89daad2b
DOI: 10.1101/2022.09.13.507815

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