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Article

The Clinical Relevance of RAS Pathway Gene Mutations in Pediatric B-Cell Acute Lymphoblastic Leukemia

2025-12-08

Abstract excerpt

<title>Abstract</title> <p> Objective High-throughput sequencing has elucidated the genetic landscape of B-cell acute lymphoblastic leukemia (B-ALL). Notably, <italic>FLT3</italic> and RAS pathway gene mutations represent a significant proportion of pediatric cases. Our study explores whether these patients have distinct clinical features and prognostic outcomes. Methods We retrospectively analyzed 562 pediatr...

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Literature Corpus work
603a2367-24e4-5029-8f53-7d3e6ddd5ea3
DOI
10.21203/rs.3.rs-8082043/v1
Open publication

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The Clinical Relevance of RAS Pathway Gene Mutations in Pediatric B-Cell Acute Lymphoblastic LeukemiaDOI 10.21203/rs.3.rs-8082043/v1
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