Article

Spectrum and Clinical Characteristics of Gene Mutations in Chinese Pediatric Acute Lymphoblastic Leukemia

2021-07-26

Abstract excerpt

<title>Abstract</title> <p>Purpose The 5-year survival rate of children with acute lymphoblastic leukemia (ALL) is 85–90%, with a 10–15% rate of treatment failure. Next-generation sequencing (NGS) identified recurrent mutated genes in ALL that might alter the diagnosis, classification, prognostic stratification, treatment, and response to ALL. Few studies on gene mutations in Chinese pediatric ALL have been iden...

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Literature Corpus work: 8d774723-5231-5b85-a86e-99a551a15e9c
DOI: 10.21203/rs.3.rs-651868/v1

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