Article

New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia

2018-09-28

Abstract excerpt

Traditionally, genetic abnormalities detected by conventional karyotyping, fluorescence in situ hybridization, and polymerase chain reaction divided childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL) into well-established genetic subtypes. This genetic classification has been prognostically relevant and thus used for the risk stratification of therapy. Recently, the introduction of genome-wide appro...

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Literature Corpus work: 3ee4fdeb-be2e-5b23-9897-2719c6b0cf23
DOI: 10.12688/f1000research.16074.1

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