Article

Exploring the Potential of Structure-Based Deep Learning Approaches for T cell Receptor Design

2024-04-24

Abstract excerpt

Deep learning methods, trained on the increasing set of available protein 3D structures and sequences, have substantially impacted the protein modeling and design field. These advancements have facilitated the creation of novel proteins, or the optimization of existing ones designed for specific functions, such as binding a target protein. Despite the demonstrated potential of such approaches in designing general...

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Literature Corpus work: 5fbba56c-da32-51c3-8965-c138ddaec55c
DOI: 10.1101/2024.04.19.590222

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