Article

The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice

2023-08-12

Abstract excerpt

Chronic exposure to persistent organic pollutants (POPs) is associated with increased incidence of type 2 diabetes, hyperglycemia, and poor insulin secretion in humans. Dioxins and dioxin-like compounds are a broad class of POPs that exert cellular toxicity through activation of the aryl hydrocarbon receptor (AhR). We previously showed that a single high-dose injection of 2,3,7,8-tetrachlorodibenzo- p -dioxin (TC...

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Literature Corpus work: f8d9e00d-4ab2-53d7-800a-7664d4eabdd8
DOI: 10.1101/2023.08.10.552760

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The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in miceDOI 10.1101/2023.08.10.552760Read

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