Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.

American journal of physiology. Endocrinology and metabolism - 1 Jan 2009

La Merrill Michele, Baston David S, Denison Michael S, Birnbaum Linda S, Pomp Daniel, Threadgill David W

Abstract excerpt

Diets high in fat are associated with increased susceptibility to obesity and metabolic syndrome. Increased adipose tissue that is caused by high-fat diets (HFD) results in altered storage of lipophilic toxicants like 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which may further increase susceptibility to metabolic syndrome. Because both TCDD and HFD are associated with increased breast cancer risk, we examined...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 9,10-Dimethyl-1,2-benzanthracene
Share to Carcinogens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Dietary Fats

Share to Mammary Neoplasms, Experimental

Share to Maternal Exposure

Share to Polychlorinated Dibenzodioxins

Share to Random Allocation

Share to Receptors, Cytoplasmic and Nuclear

Source

Open in PubMed Open full text

Identifiers

PMID: 18840765
DOI: 10.1152/ajpendo.90368.2008
PMCID: PMC2636987

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mouse breast cancer model-dependent changes in metabolic syndrome-associated phenotypes caused by maternal dioxin exposure and dietary fat.PMID 18840765Read ↗

Gestational Cd Exposure in the CD-1 Mouse Induces Sex-Specific Hepatic Insulin Insensitivity, Obesity, and Metabolic Syndrome in Adult Female OffspringSemantic proximity Read ↗

In utero exposure of rats to high-fat diets perturbs gene expression profiles and cancer susceptibility of prepubertal mammary glands.Semantic proximity Read ↗

Maternal metabolic perturbations elicited by high-fat diet promote Wnt-1-induced mammary tumor risk in adult female offspring via long-term effects on mammary and systemic phenotypes.Semantic proximity Read ↗

Prenatal Bisphenol A Exposure in Mice Induces Multi-tissue Multi-omics Disruptions Linking to Cardiometabolic DisordersSemantic proximity Read ↗

Endocrine-Mediated Mechanisms of Metabolic Disruption and New Approaches to Examine the Public Health ThreatSemantic proximity Read ↗

Glucoregulatory Reprogramming in Male Mice Offspring Induced by Maternal Transfer of Indoor Flame Retardant Endocrine DisruptorsSemantic proximity Read ↗

Prolonged low-dose dioxin exposure impairs metabolic adaptability to high-fat diet feeding in female but not male miceSemantic proximity Read ↗

Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis.Semantic proximity Read ↗

Perinatal lead (Pb) exposure results in sex-specific effects on food intake, fat, weight, and insulin response across the murine life-course.Semantic proximity Read ↗

Maternal transfer of environmentally relevant polybrominated diphenyl ethers (PBDEs) produces a diabetic phenotype and disrupts glucoregulatory hormones and hepatic endocannabinoids in adult mouse female offspringSemantic proximity Read ↗

Cisplatin exposure alters long-term metabolic phenotype of male, but not female, high-fat diet-fed miceSemantic proximity Read ↗

Transgenerational metabolomic fingerprints in mice ancestrally exposed to the obesogen TBTSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.