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Early, sex-dependent and progressive proteomic imbalance in the amygdala during Alzheimers disease progression

2025-12-01

Abstract excerpt

<h4>Background</h4> The amygdala is involved in the emotional expression, memory processing and managing stimulatory input. Although amygdala atrophy is early evidenced in Alzheimer’s Disease (AD), the molecular mechanisms disrupted in initial neuropathological stages are still unknown. In the present study, we investigated the proteomic impairment of the amygdaloid region from AD-Braak stage I-II and III-IV subj...

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Literature Corpus work
5f74a426-5e52-5cb3-aed6-b552e13549fe
DOI
10.1101/2025.11.26.690815
Open publication

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Early, sex-dependent and progressive proteomic imbalance in the amygdala during Alzheimers disease progressionDOI 10.1101/2025.11.26.690815
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