Article
Neuropathological stage-dependent proteome mapping of the olfactory tract in Alzheime’s disease: From early olfactory-related omics signatures to computational repurposing of drug candidates
2023-10-02
Abstract excerpt
<h4>ABSTRACT</h4> Alzheimer’s disease (AD) is the most common form of dementia, characterized by an early olfactory dysfunction, progressive memory loss and behavioral deterioration. Albeit substantial progress has been made in characterizing AD-associated molecular and cellular events, there is an unmet clinical need for new therapies. In this work, olfactory tract proteotyping performed in controls and AD subje...
Topics
Open a Topic to create a Post that cites this publication.
- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Bioinformatics and Genomic Networks
- Diet and metabolism studies
- Metabolomics and Mass Spectrometry Studies
- Neurological Disease Mechanisms and Treatments
- Olfactory and Sensory Function Studies
- Parkinson's Disease Mechanisms and Treatments
Identifiers and source
- Literature Corpus work
- c2fa972e-1496-5a9a-8420-3735c1b6527e
- DOI
- 10.1101/2023.10.01.560342
