Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Association of lipids and lipid-lowering drugs with peripheral arterial disease: A Mendelian randomization study.

Journal of clinical lipidology - 1 Jan 2024

Tao Mengjun, Zhang Yuanxiang, Li Qi, Feng Xuebing, Ping Cheng

Abstract excerpt

BACKGROUND: It remains unclear whether lipid profiles and lipid-lowering medications are causally related to peripheral arterial disease (PAD). OBJECTIVE: Explain whether there is a causal relationship between lipid status and lipid-lowering drugs and PAD. METHODS: In this two-sample Mendelian randomization (MR) analysis, we assessed the causal relationship between lipid traits, including high-density lipoprotein...

Topics

Humans
Mendelian Randomization Analysis
Peripheral Arterial Disease
Hypolipidemic Agents
Lipids
Proprotein Convertase 9
Polymorphism, Single Nucleotide
Cholesterol, LDL
Male
Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39304430
DOI: 10.1016/j.jacl.2024.06.007

Genes

APOB
PCSK9
HMGCR
NPC1L1
APOA1
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of lipids and lipid-lowering drugs with peripheral arterial disease: A Mendelian randomization study.PMID 39304430Read ↗

Factorial Mendelian randomization of lipoprotein (a) lowering, low-density lipoprotein cholesterol lowering, and lifestyle improvements: joint associations with cardiovascular risk.Semantic proximity Read ↗

Apolipoprotein and peripheral artery disease: Mendelian randomization analysis.Semantic proximity Read ↗

Associations of Lipid-Lowering Drugs With Blood Pressure and Fasting Glucose: A Mendelian Randomization Study.Semantic proximity Read ↗

The associations of plasma phospholipid arachidonic acid with cardiovascular diseases: A Mendelian randomization study.Semantic proximity Read ↗

Mendelian Randomization Reveals the Role of HMGCR in Pulmonary Arterial Hypertension Treatment, Independent of LDL Cholesterol ConcentrationSemantic proximity Read ↗

Genetic determinants of lipids and cardiovascular disease outcomes: a wide-angled Mendelian randomization investigationSemantic proximity Read ↗

Genetic Determinants of Lipids and Cardiovascular Disease Outcomes: A Wide-Angled Mendelian Randomization Investigation.Semantic proximity Read ↗

Lipid-lowering and antihypertensive drugs on aortic disease risk: insights from Mendelian randomization analysis and real-world pharmacovigilance data.Semantic proximity Read ↗

Association of genetic variants related to combined lipid-lowering and antihypertensive therapies with risk of cardiovascular disease: 2 × 2 factorial Mendelian randomization analyses.Semantic proximity Read ↗

Drug targets for lipid modification and risk of type 2 diabetes: a cis-Mendelian randomization study.Semantic proximity Read ↗

Lipid-lowering therapies for aortic stenosis: a drug-target Mendelian randomization study.Semantic proximity Read ↗

Mendelian randomization study on insulin resistance and risk of hypertension and cardiovascular disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.